Introduction. Pharmacy organizations as an element of the healthcare system are certainly called upon to perform a social function - ensuring the health of citizens, at the same time, it is necessary to understand what costs the owner will incur when opening, and in what time frame the pharmacy will be able to reach not only self-sufficiency, but also to obtain a profit target. It is also advisable to determine the specifics of the pharmacy organization (portrait of the target audience - consumers of this particular organization, location, infrastructure, analyze the competitive environment and identify advantages, etc.) and organize work in accordance with it. Aim. To carry out forecasting of financial indicators and target audience on the example of a pharmacy organization opened near a skin and venereological dispensary. Materials and methods. The analysis of the target audience, the calculation of costs, profits and payback period on the example of a pharmacy organization opened near a skin and venereological dispensary, the "cost constructor for opening a pharmacy organization" is proposed. The research uses methods of content analysis, generalization, observation, questioning and modeling. The calculations were carried out taking into account the cost of premises, equipment and assortment items on the example of a pharmacy organization in Moscow with data for March 2023. Results. The results of the conducted surveys suggest the expediency of opening a pharmacy organization with an expanded range of care cosmetics, products for skin care of the body and face, and an assortment of dermatological preparations focused on medical appointments. According to the results of calculations using the proposed "constructor", the estimated cost of opening an organization was 3,883,890.00 rubles; monthly costs - 511,000.00 rubles; monthly net profit amounted to 346042,22 rubles, the payback period of the simulated pharmacy organization is expected to be 11 months. Discussion. The proposed constructor for calculating the costs of opening a pharmacy organization is a "flexible" table reflecting the list of necessary documents, a list of equipment, materials indicating their approximate cost as of March 2023. In the course of the study, such indicators as the monthly patient flow, the main nosologies that patients treat, the most frequently prescribed medications, which determine the portrait of a potential pharmacy visitor and help form the starting assortment of medicines and pharmacy products, were determined. Conclusion. The analysis of the target audience, calculation of costs, profits and payback period on the example of a pharmacy organization opened near a skin and venereological dispensary was carried out. The constructor developed in this work can be used to predict costs when opening or reprofiling a pharmacy organization. Also, to assess the feasibility of opening a pharmacy organization, it is possible to use the survey of doctors and pharmaceutical specialists proposed in the work as an example.