Introduction: The organization of proper quality control of medicinal raw materials and finished products in accordance with the requirements of the GMP standard is one of the strategic tasks, the solution of which will radically change the state of affairs in this extremely important industry for the state. Quality control means carrying out tests and tests using methods, materials and equipment described in pharmacopoeial monographs or special regulatory documents. Objective: to analyze the quality control of the developed drug based on nanoparticles using the Shewhart control chart. Materials and methods: UV spectrophotometer SF-2000, induction levitation melting, active ingredients dioxomethyltetrahydropyrimidine, vaseline, lanolin. Results: a scheme for the production of a medicinal ointment based on dioxomethyltetrahydropyrimidine and a method for its quantitative determination were developed, and Shewhart's control chart was obtained. Discussions: The quantitative determination of the developed ointment with nanoparticles was carried out by UV spectrophotometry, according to the method of comparison with a standard sample. The content of the substance was within the normal range, as evidenced by Shewhart's control charts. Conclusion: this ointment meets the standards and can be used for preclinical studies in order to identify a tendency to treat photodermatitis, ulcers, pressure sores.