Introduction. The high prevalence of comorbid pathology, especially in old age, is an important problem in gerontology and geriatrics. The presence of such pathology in patients leads to a rapid pace of natural aging processes, leading to premature aging of the body and an increase in biological age. The prevalence of metabolic syndrome continues to increase worldwide and is associated with both the aging population and the increasing incidence of obesity and lifestyle changes, thereby increasing the risk of overall morbidity and mortality. Purpose of the study. To study indicators of biological age and anthropometric data of patients with arterial hypertension against the background of metabolic syndrome in middle and old age. Materials and methods. The examination was carried out on 38 patients diagnosed with arterial hypertension against the background of metabolic syndrome in middle and old age. During the study, an analysis of the anthropometric characteristics of patients (weight, height, WC, BMI) and a study of biological age were carried out using the method of V.P. Voitenko. Statistical research methods were used to analyze the data obtained. The normality of the distribution of quantitative indicators was assessed using the Shapiro-Wilk test. For the studied quantitative indicators, average values were calculated. Student's t test was used to compare mean values. The correlation was assessed using the Spearman rank correlation method. Results. Of the 38 examined patients with arterial hypertension against the background of metabolic syndrome, the vast majority had I degree obesity. Indicators of actual biological age among all examined patients significantly exceeded its proper values. The relationship between the data of the actual biological age and the weight and WC indicators of the patients was revealed. Discussions. Aging of the body is a complex dynamic and inevitable process. Premature aging is characterized by an early decline in many body functions. A number of chronic diseases contribute to premature aging. Metabolic syndrome is a complex pathology that includes disorders of carbohydrate and lipid metabolism, abdominal obesity and arterial hypertension. The presence of such pathology in middle-aged and elderly patients significantly accelerates the natural rate of aging. Conclusion. The prevalence of both obesity and aging has increased dramatically in society. Abdominal obesity is an important risk factor for the development of premature aging of the body, which generally leads to a deterioration in the quality of life of such patients. Biological age is a common model for assessing function in aging individuals because it can provide a more accurate estimate of a person's degree of aging than calendar age.