Background. Sarcopenia and cognitive impairment are widespread geriatric syndromes nowadays. However, the relationship between sarcopenia, cognitive functions and physical activity has not been fully studied. Aim: to study the relationship between sarcopenia, cognitive functions and physical activity in elderly and senile people. Materials and methods. The study involved 386 people over the age of 60 (average age 80.30±9.18 years). Complaints, life history, diseases, and anthropometric data were collected from all study participants. The nutritional status was determined using the short form of the nutrition assessment scale (MNA-SF). Body composition was assessed using the bioimpedance method on the ABC-02 device (Medass, Russia), handgrip strength with a hand dynamometer (DK-50, Russia), walking speed according to the standard method, cognitive functions using a mental status questionnaire (MMSE). Results: The prevalence of cognitive impairment was 45.3%, the prevalence of sarcopenia was 49.7%. In the group with cognitive impairment, sarcopenia was observed in 54.7% of patients (p