Introduction. The new coronavirus infection pandemic has had a significant impact on the population’s appeal and an increase in emergency medical calls around the world. The purpose of the study is to assess the performance indicators of the emergency medical department of the closed administrative-territorial entity of the city of Zelenogorsk during the COVID-19 pandemic. Materials and methods. Observational descriptive-evaluative study for the period from 2019 to 2021 was carried out in the Krasnoyarsk Territory in the service area of the Federal Siberian Scientific and Clinical Center of the FMBA of Russia. The main source of information was data from federal statistical observation forms (No. 30), as well as emergency notifications of disease cases (form No. 058/u), based on which the performance indicators of the emergency medical service in the serviced area were assessed. Results. For the analyzed period 2019 - 2021 in the Zelenogorsk 63,211 calls to emergency medical teams were made, and medical care was provided to 59,728 patients, of which 66.9% of patients sought medical help during 2020-2021. In the first year of the pandemic, the average daily number of emergency medical calls increased by 31.9%. Among patients seeking medical help, the proportion of the population over working age has increased. The main reasons for the population to seek emergency medical care were diseases of the circulatory system (31.36%) and diseases of the respiratory system (14.92%). The share of patients delivered by mobile ambulance teams to medical organizations for examination and treatment in a hospital setting increased from 21.7% in 2019 to 24.3% in 2021, and the number of intra-hospital transports using ambulance vehicles increased by 2.2 times from 2019 to 2021. The increase in load contributed to a decrease in the proportion of calls with a travel time of 20 minutes, which required organizational measures aimed at increasing the availability of emergency medical care for the population. Conclusions. The organizational measures made it possible to increase the number of visiting teams (shifts) during the period of active spread of the COVID-19 infection and to provide the population served with accessible emergency medical care in the required volume.