Introduction. Acute cerebrovascular diseases (CVD) are one of the main causes of long-term disability and mortality in developed countries. In recent years, modern methods of prevention, treatment and rehabilitation of patients with CVD have been widely implemented in different regions of the country, therefore, analysis of the dynamics of disability and mortality in this nosology is of considerable interest. Purpose. To analyze the rates of disability and mortality in acute CVD in the Republic of Bashkortostan for the period 2014-2023. Materials and Methods. We analyzed the incidence of acute CVD according to the annual report of the Republic of Bashkortostan in the form of FSN № 12 “Information on the number of diseases registered in patients living in the service area of the medical organization”. Results. Disability due to brain infarction in the Republic of Bashkortostan was maximal in 2014 - 161 cases. During the analyzed period there was a tendency to decrease disability in this disease, it decreased by 10.8 times. Mortality from acute CVD in the Republic of Bashkortostan ranged from 85.6-47.2 cases per 100 thousand population. The highest rates were observed in 2016 - 85.7 cases per 100 thousand population, in subsequent years this indicator decreased to 50-60 cases per 100 thousand population. Discussion. Mortality from acute CVD in the Republic of Bashkortostan was 1.5-2 times lower than in the Russian Federation as a whole, where this indicator was 88-93 cases per 100 thousand population, reflecting implementation of different measures. Conclusions. Mortality and disability from acute CVD in the Republic of Bashkortostan is probably due to the wide implementation of clinical recommendations in practice, increased accessibility of medical care, as well as the implementation of the regional program to reduce mortality from cardiovascular diseases.