Introduction. Modern pharmaceutical manufacturing companies operate in conditions of strict requirements of international quality standards and high competitiveness. The corporate culture formed by top management is a critical factor in ensuring the effectiveness of the quality management system. Aim. The study of the priority value orientations of top management as a factor in the formation of corporate identity of personnel in pharmaceutical companies. Materials and Methods. System analysis, socio-psychological survey- a survey of top management of manufacturing and distribution pharmaceutical companies in St. Petersburg. Results and discussions. Top management recognizes the significant impact of corporate culture on the performance of the quality management system. A gap has been found between the declared values and their articulation in practice. The highest priority is given to the values of product quality and safety, while social responsibility, as a fundamental value, is on the periphery. Insufficient attention to the professional development of staff has been revealed, with an external declaration to the contrary. Conclusions. The formation of a corporate culture based on the values of quality, safety and innovation, while increasing attention to professional development and social responsibility, can become a factor in improving the effectiveness of the quality management system and the competitiveness of pharmaceutical companies.