Фтизиатрия
EPIDEMIOLOGY OF TUBERCULOSIS IN CHILDREN
Aksenova V.A.1, Sterlikov S.A.2,3, Belilovskiy E.M.4, Kazykina T.N.2, Rusakova L.I.3
1. National Medical Research center of Phtisiopulmonology and infectious diseases, Moscow, Russian Federation
2. Federal Research Institute for Health Organization and Informatics of Ministry of Health of the Russian Federation, Moscow, Russian Federation
3. Central TB Research Institute, Moscow, Russian Federation
4. Moscow Research and Clinical Center for Tuberculosis Control, Moscow Health Department, Moscow, Russian Federation
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Summary:
Introduction. The incidence of children is an important characteristic of the tuberculosis epidemic situation. The purpose of the work is to assess the current state and dynamics of the epidemic situation of tuberculosis in children in Russian Federation.
Materials and methods. Studied official statistics. In some cases, to reduce the stochastic effects, indicators were calculated over more than one-year observation periods. When analyzing the indicators, 95% confidence intervals were calculated, the statistical significance of the differences was determined.
Results and discussion. Over the past five years, there has been a decrease in the notification rate of tuberculosis from 16.4 to 9.6 per 100,000 children 0–14 years old. The tuberculosis notification rate for children under one year remains constant. The notification rate of tuberculosis in children in the eastern regions of Russia is highest. When calculating the incidence ratio of children and adults, there is a high variation of values from 0.04–, 0.1 to 0.3–0.7, which makes it possible to analyze hyper- and hypodiagnostic of tuberculosis in children. The tuberculosis notification rate for children 15–17 years old is twice as high as that of children 0–14 years old, but significantly lower than the indicator for adults 18–24 years old. In the last 6 years, there has been a decrease in this indicator for children aged 15-17 years. The proportion of patients with bacterial excretion among children increasein older age groups: 5–6 years (3.0%), 7–14 years (8.4%), 15–17 years (25.8%). Among the extra-respiratory forms of tuberculosis, bone- and joint tuberculosis predominates (41.7%). There is a seasonal irregularity in the coverage of 0–17-year-old children with preventive examinations for tuberculosis, due to limitations of the method of immunodiagnosis of tuberculosis and social reasons. There is a seasonal decline in the notification rate of tuberculosis in children in January and August, and a statistically significant increase in April. The prevalence of tuberculosis among children and adolescents between the ages of 0–17 years, since 2009, has decreased annually, and in 2017 was 14.1 per 100 thousand children 0–17 years old. The proportion of children with tuberculosis combined with HIV is increasing; moreover, it is higher among children 0–14 years old than among children 15–17 years old (3.6 and 0.7%). The death rate of children aged 0–14 years from tuberculosis in 2017 was 0.03, and 15–17 years old - 0.1 per 100,000 children of the corresponding age. There is a decrease in the mortality rate mainly in children over 10 years. The number of children aged 0–14 with newly registered residual changes after tuberculosis in the last two years exceeded the number of newly diagnosed children with tuberculosis. There is a high notification rate for children from contact with patients with tuberculosis with bacterial excretion (382.7) and hyperergic tests (266.3).
Conclusion. Currently, there is a persistent positive dynamics of the epidemic situation on tuberculosis in children, manifested in a decrease in the tuberculosis notification rate for children, the prevalence of tuberculosis in children, and infant mortality from tuberculosis. The analysis made it possible to identify a number of epidemiological features of the disease, allowing to improve the detection of tuberculosis among children.
Keywords tuberculosis in children and adolescents, epidemiology of tuberculosis, age-related features of tuberculosis, incidence of tuberculosis in children.
Bibliographic reference:
Aksenova V.A., Sterlikov S.A., Belilovskiy E.M., Kazykina T.N., Rusakova L.I., EPIDEMIOLOGY OF TUBERCULOSIS IN CHILDREN // Scientific journal «Current problems of health care and medical statistics». - 2019. - №1;
URL: http://healthproblem.ru/magazines?textEn=218 (date of access: 21.12.2024).
URL: http://healthproblem.ru/magazines?textEn=218 (date of access: 21.12.2024).
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