Despite the improvement of the diagnostic examination, the number of glaucoma patients remains high. At the same time, morphometric and functional indicators in glaucomatous patients of different ages remain insufficiently studied. The aim of the study - study the features of morphometric and electrophysiological parameters in glaucoma in middle-aged and elderly patients. Materials and methods: On the basis of the Tambov branch of the ISTC "eye microsurgery named after academician S. N. Fedorov" in 2018-2019, a survey of patients 45-59 years old and 60 patients 60-74 years old with primary open-angle glaucoma of the 2nd-3rd stage was conducted. The fields of vision were determined using a white stimulus Foerster, pattern electroretinography on the Tomey EP-1000 device, and computer statistical perimetry on the EP-1000 PRO Multifocal device. The reliability of differences was determined by the X2 criterion. Results of the study: in elderly patients, a significantly high proportion of absolute cattle (19.2±0.3% vs. 9.7±0.4%) and 1st-order cattle (16.8±1.3% vs. 10.2±1.2%), a significant reduction in the amount of visual fields along the 8 meridians, and especially on the temporal and upper-temporal ones, was found. Among electrophysiological disorders, the latency of the a-wave increased significantly to 19.8±2.1 MS in the elderly and 10.3±0.9 MS in the middle age, the amplitude of the b-wave-115.6±2.3 mV and 54.8±2.6 mV in the middle age. Conclusion: Glaucoma in old age occurs with more significant violations of morphometric and electrophysiological parameters.