Acute myocardial infarction is an important gerontological problem and to solve it, it is important to predict this pathology. The aim of the study was to predict acute myocardial infarction in the elderly population depending on common diseases of the cardiovascular system. Materials and Methods: a retrospective study of the morbidity of the elderly population with leading nosologies of the cardiovascular system was conducted according to official state statistics. To predict the frequency of acute myocardial infarction in the elderly population, the regression method and the program "Statistica 10.0" were used. Results of the study: based on the results obtained, prognostic methods were developed that allow predicting the incidence of acute myocardial infarction in the elderly with a high error-free probability, taking into account the prevalence of the main forms of cardiovascular diseases in the study region. Predictive models have a linear relationship and are adequate according to the Fisher criterion. Conclusion: the developed prognostic models should be used in gerontological practice to improve cardiology services in the region.