Introduction. The prognosis for heart failure remains poor and the mortality rate is high, regardless of the existing advances in treatment. An important component of treatment is drug therapy. The real situation of outpatient therapy for patients with CHF remains poorly understood. In this connection, the study of outpatient therapy for patients with CHF is an actual task. Objective: to study the scope of prehospital drug therapy in patients with decompensated CHF. Materials and methods: included 107 patients aged 46-95 years with decompensated CHF functional class III-IV (FC). 4 groups were formed: 1st - 29 people. (53.9 ± 4.5 years old) middle age (46-60 years old); 2nd - 31 people (68.3 ± 5.0 years) elderly (61-74 years); 3rd - 40 people (81.5 ± 4.1 years) old age (75-89 years). 4th - 7 people (92.4 ± 1.4 years) of the age of centenarians (> 90 years). Patients underwent: examination, electrocardiography (ECG), echocardiography (EchoCG), coagulogram with determination of the level of international normalized ratio (INR). Results: there was a significant decrease in the number of patients with reduced ejection fraction (EF) (p = 0.03) and an increase in the number with preserved EF (50% or more) (p = 0.02) with increasing age. There was an increase in the number of patients receiving digoxin (