Introduction. A number of factors of unfavorable outcome in the acute of chronic heart failure (AHF) have been identified according to research data. The role of geriatric syndromes as predictors of mortality in elderly patients with AHF has not been sufficiently studied. Assessment of the syndrome of senile asthenia as a marker of mortality in patients with AHF in the intensive care unit (ICU) is relevant. Objective: to evaluate and identify the most significant predictors of mortality and prolonged ICU stay in patients with AHF. Materials and methods: 107 patients aged 46-95 years with AHF functional class III-IV were included. 4 groups were formed: 1st - 29 people (53.9 ± 4.5 years), middle age (46-60 years); 2nd - 31 people (68.3 ± 5.0 years) elderly (61-74 years); 3rd - 40 people (81.5 ± 4.1 years) old age (75-89 years). 4th - 7 people (92.4 ± 1.4 years) of the age of centenarians (> 90 years). The patients underwent: examination, echocardiography. Geriatric syndromes were assessed using a comprehensive geriatric assessment (CGE) using the Specialized Geriatric Examination program. Results. The longest duration in ICU was in the old age group- 5.13 ± 1.9 days. Mortality in the ICU on the 1st day was 1.07%, over the whole period - 14%. The most significant independent predictors of mortality in ICU (OR [95% CI]) were terminal stage of CHF (52.5 [4.62; 1419.34], p