Introduction. According to the World Health Organization, in 2030, people aged 60 years and older will make up one sixth of the world's inhabitants. By this time, their number will increase to 1.4 billion. But the population of elderly people is heterogeneous. The main problem of elderly and senile people, which leads to disability, is the syndrome of senile asthenia. Senile asthenia syndrome is a clinical condition in which a person's vulnerability to the development of diseases and/or mortality increases when exposed to a stressor. One of the assessment methods for asthenia or senile asthenia syndrome is the measurement of hand strength (dynamometry). The strength of the hand largely corresponds to the assessment of simultaneous overall strength, upper limb function, bone mineral density, risk of fractures, falls, nutritional deficiencies, cognitive impairment, depression, sleep problems, diabetes, multimorbidity and quality of life. Goal. Assessment of the strength of the hand in elderly and senile patients – the indigenous population of the Republic of Adygeya (Adygeis). Materials and methods. During the research work, 184 patients (84 men and 100 women) aged 65 to 93 years were examined. The study involved indigenous residents of the Republic of Adygeya who identify themselves as Adygeis. All participants were divided into age groups: 65-69, 70-74, 75079, 80-84, 85-89, 90 years and older. Patients undergoing outpatient and inpatient treatment at the State Medical Institution of the Republic of Armenia "Adygeya Interdistrict Hospital named after K.M.Batmen", GBUZ RA "Adygeya Republican Clinical Hospital", GBUZ RA "Maikop Clinical Hospital", wrist dynamometry of both hands was performed using a dynamometer MEGEON-34090. Dynamometry of each hand was carried out three times with fixing the average value of the sum of three measurements. The study did not involve patients with severe acute or chronic diseases, injuries (acute cerebrovascular accident, acute coronary syndrome, injuries of the musculoskeletal system, condition after surgical treatment). Results. Thus, the data obtained differ from the few available Russian epidemiological studies and foreign ones. This indicates that there cannot be universal recommended reference values for the entire population of the Russian Federation, given its multinational composition. The difference with the data obtained in the North-Western part of the country cannot be considered pathological for the indigenous population of the Republic of Adygeya. A large-scale regional epidemiological study is needed for this region in order to obtain local normative values of carpal dynamometry. But the importance of hand strength as a predictor of senile asthenia is unconditional. Conclusions. Summing up, we can say that the strength of a hand as a predictor of senile asthenia syndrome is important in the diagnostic practice of therapists, geriatricians. But for the analysis, control figures of the normal values of dynamometry for each age category are needed. Our study is the first in the territory of the Republic of Adygeya, which can become the basis for the formation of regional recommendations for the diagnosis of senile asthenia in the indigenous population of the Republic of Adygeya (Adygeis) by determining the strength of the hand.