Introduction. The increase in the average life expectancy of the population makes the problem of geroprotection and treatment of diseases associated with the achievement of elderly and senile age by patients more urgent. In search of a solution to this problem, there is a growing interest in the study of biologically active peptides. The biological properties of many representatives of this group of organic compounds allow us to consider them a promising basis for the creation of new medicines that are interested for geriatric practice. Therefore, the analysis of the biological properties of these peptides seems relevant and practically significant. Research objectives were analysis of the current literature data on the properties of biologically active peptides of interest for geroprotection and geriatric practice Materials and methods. Scientific methods of theoretical research (analysis, synthesis, induction, deduction, etc.) were used. The biological properties of peptides that may be useful for the purposes of geroprotection, as well as for the treatment of diseases and conditions that most often occur in the elderly and senile cases were analyzed. The data for the study were obtained from the open sources that are indexed by the databases of Scopus, Web of Science, MedLine, The Cochrane Library, EMBASE, Global Health, CyberLeninka, and RSCI. Results and their discussion. Biologically active peptides have been found to have many effects of interest to geriatric practice. In particular, some representatives of this group of organic compounds have a geroprotective effect. The properties of biologically active peptides are also known to help eliminate dyslipoproteidemia, protect against oxidative stress, normalize blood pressure, preserve bone mineral density, prevent and treat malignant tumors, eliminate disorders of carbohydrate metabolism, and slow down skin aging. Conclusion. The analysis of the literature data indicates that biologically active peptides have a serious potential in the field of achieving geroprotection. In addition, this group of organic compounds may be the basis for the development and creation of new, more effective and safe methods for the prevention and treatment of chronic non-communicable diseases that are often found in geriatric practice.